Surgical Management of Patients with Diabetic Foot Ulcers at MOI Teaching and Referral Hospital, Eldoret, Kenya
DOI:
https://doi.org/10.14738/bjhr.1304.11865Keywords:
Amputation, Body mass index, Debridement, Diabetic foot Ulcer, Glycated haemoglobin, Neuropathy, Surgical managementAbstract
Background: The Diabetic Foot Ulcer (DFU) is a break in epidermis below ankle in person with Diabetes Mellitus (DM). The prevalence of this disorder is increasing and there is a 15% chance in lifetime of a diabetes mellitus patient developing it. The worldwide prevalence of DFUs has been estimated to be between 4% - 17%. In Kenya, diabetes has a prevalence of 3.3 % - 10%. It is a public health problem particularly in developing countries. DFU is due to neuropathy and poor blood circulation, which can progress to complications such as gangrene and infection, which are attributed to late presentation, poor awareness both among healthcare workers and patients, as well as late referral once they occur. The management of patients faces many challenges though the combination of nonoperative and operative strategies are in use. There is paucity of publication locally, hence the need for this study. Objective: To evaluate the surgical management of patients with diabetic foot ulcers at Moi Teaching and Referral Hospital (MTRH), Eldoret, Kenya. Methods: A cross sectional study done in the surgical wards and the diabetic clinic of MTRH between 1st May 2017 and 31st April 2019, involving census of 89 adult patients with diabetic foot ulcers who met the inclusion criteria. Characterization of these patients had been previously done by same team of authors. Relevant data regarding the management with particular interest in treatment modality, and association between some risk factors (peripheral neuropathy, body mass index and glycated haemoglobin) and treatment modality was collected using interviewer administered questionnaires. Data was then cleaned, coded and analyzed using statistical package (SPSS version 19). Presentation was in diagrammatically and in prose formats. Results: The 89 patients were graded using Wagner’s classification: grade 1- 4 were 19, 30, 28 and 12 respectively. Debridements were done to 78 (87.6%) while amputation to 11 (12.4%). Of factors associated with surgical management (debridement and amputation), statistically significant findings (p<0.05) were for peripheral neuropathy (pricking and weakness). However, there was no statistically significant association between body mass index and surgical treatment as well as glycated haemoglobin and surgical treatment. Conclusion: Grade 2 DFUs was the commonest. Debridements were done in most patients, while eleven patients with grade 4 were done amputations. Association between surgical management and peripheral neuropathy was statistically significant. Recommendations: Creating public awareness, early identification of DFUs in patients and appropriate management to salvage the foot are necessary to prevent progression into stage requiring amputation. Multidisciplinary team approach should be adopted.
References
Adler, A. I., Erqou, S., Lima, T. A. S., & Robinson, A. H. N. (2010). Association between glycated haemoglobin and the risk of lower extremity amputation in patients with diabetes mellitus-review and meta-analysis. Diabetologia, 53(5): 840–849. https://doi.org/10.1007/s00125-009-1638-7.
Armstrong, D., & Lipsky, B. (2004). Diabetic foot infections: Stepwise medical and surgical management. International Wound Journal, 1(2): 123–132. https://doi.org/10.1111/j.1742-4801.2004.00035.x.
Armstrong, D. G., Nguyen, H. C., Lavery, L. A., Van Schie, C. H., Boulton, A. J., & Harkless, L. B. (2001). Offloading the diabetic foot wound: a randomized clinical trial. Diabetes Care, 24(6): 1019–
Barth, R., Campbell, L. V., Allen, S., Jupp, J. J. & Chisholm, D. J. (1991). Intensive Education Improves Knowledge, Compliance, and Foot Problems in Type 2 Diabetes. Diabetic Medicine, 8(2): 111-117.
Bauman, J. H., & Brand, P. W. (1963). Measurement of pressure between foot and shoe. The Lancet, 281(7282): 629–632.
Bergtholdt, H. T. & Brand, P. W. (1976). Temperature assessment and plantar inflammation. Lepr Rev, 47(3):211-9. doi: 10.5935/0305-7518.19760032. PMID: 966949.
Bloomgarden T, Z., Karmally, W., Metzger, J., Brothers, M., Nechemias, C., Bookman, J., Faierman, D., Ginsberg-Fellner, F., Rayfield, E., & Brown, V. W. (1987). Randomized controlled trial of ddiabetic patient education: Improved knowledge without improved metabolic status. Diabetes Care, 10(3): 263–272.
Boulton, A. J. M. (2004). The diabetic foot: From art to science. The 18th Camillo Golgi lecture. Diabetologia, 47(8): 1343–1353. https://doi.org/10.1007/s00125-004-1463-y.
Boulton, A. J. M. (2008). The diabetic foot: grand overview, epidemiology and pathogenesis. Diabetes Metabolism Research and Reviews, 24(supplement 1): s3–s6.
Boulton, A. J. M., Balducci, Stefano, Sacchetti, Massimo, Haxhi, Jonida, Orlando, Giorgio, D’Errico, Valeria, Fallucca, Sara, Menini, Stefano, Pugliese, G., Tunis, B., Barth, R., Campbell, L. V., Allen, S., Jupp, J. J., Chisholm, D. J., Armstrong, D. G., Nguyen, H. C., Lavery, L. A., Van Schie, C. H. M., Boulton, A. J. M., Harkless, L. B., Lipsky, B. A., Bakker, K., Apelqvist, J., Schaper, N. C., Adler, A. I., … Archibald, L. K. (2004). Practical guidelines on the management and prevention of the diabetic foot 2011. Diabetes/Metabolism Research and Reviews, 47(2): 1019–1022. https://doi.org/10.2337/diacare.24.6.1019.
Boulton J.M, A., Kirsner S, R., & Vileikyte, L. (2004). Neuropathic diabetic foot ulcers. New England Journal Of Medicine, 351(1): 48–55.
Brem, H., Sheehan, P., & Boulton J.M, A. (2004). Protocol for treatment of diabetic foot ulcers. The American Journal Of Surgery, 187(supplement): 1s-10s.
Burns, S., & Jan, Y.-K. (2012). Diabetic foot ulceration and amputation. INTECH Open Access Publisher. http://cdn.intechopen.com/pdfs-wm/37901.pdf.
Cardinal, M., Eisenbud E, D., Armstrong G, D., Zelen, C., Driver, V., Attinger, C., Phillips, T., & Harding, K. (2009). Serial surgical debridement: A retrospective study on clinical outcomes in chronic lower extremity wounds. Wound Repair and Regeneration, 17(3): 306–311. Scholar Publishing
Connor, H. (2008). Some historical aspects of diabetic foot disease. Diabetes/Metabolism Research and Reviews, 24(S1): S7–S13. https://doi.org/10.1002/dmrr.838.
Davis, W. A., Norman, P. E., Bruce, D. G., & Davis, T. M. (2006). Predictors, consequences and costs of diabetes-related lower extremity amputation complicating type 2 diabetes: the Fremantle Diabetes Study. Diabetologia, 49(11): 2634–2641. https://doi.org/10.1007/s00125-006-0431-0.
Giacalone, V. (2006). Offloading the diabetic foot. In: Continuing Medical Education, Podiatry Management, pages 253-264. http://podiatrym.com/cme/Mar 06 CME2.pdf.
Harrison, T. , Rescnick, W. , Wintrobe, M. , Thorn, G. , Adams, R. , Beeson, P.B., Bennet I.L. J., E, B., Isselbacher, K. J., Petersdorf, R. G., Wilson, J. D., Martin, J. B., Fauci, A. S., Root, R., Kasper, D. L., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (2015). Harrison’s principles of internal medicine (19th ed.). McGraw Hill Education.
Jones L.E, T. (2013). Diabetes Mellitus:The increasing burden of disease in Kenya. South Sudan Medical Journal, 6(3): 60-64.
Katherine A, G., Elizabeth A, L., Marjana, T.-C., & Robert s, K. (2012). The role of surgical debridement in healing of diabetic foot ulcers. Skinmed, 10(1): Lepantalo, M., Apelqvist, J., Setacci, C., Ricco, J. B., DeDonato, G., Becker, F., Robert-Ebadi, F., Cao, P., Eckstein, H. H., DeRango, P., Diehm, N., Schmidli, J., Teraa, M., Moll, F. L., Dick, F., &
Davie, A. H. (2011). Diabetic foot. European Journal Of Vascular Endovascular Surgery, 42(2): 60–
Moi Teaching and Referral Hospital website (2021). About us. Available at: https://www.mtrh.go.ke/?page_id=14
Morgan, N. (2013). What you need to know about hydrogel dressings. http://woundcareadvisor.com/apple-bites-vol2-no6/.
Moulik K, P., Mtonga, R., & Gill G, G. (2002). Amputation and mortality in new onset diabetic foot ulcers stratified by etiology. Diabetes Care, 26(2): 491–494.
Nyamu, P. N., Otieno, C. F., Amayo, E. O., & Mcligeyo, S. O. (2003). Risk factors and prevalence of diabetic foot ulcers at Kenyatta National Hospital , Nairobi, East African Medical Journal, 80(1): 36–
Obare, K. S., Aumba, B. R. & Ongaro, N. (2026). Characterization of patients with diabetic foot ulcers managed at Moi Teaching and Referral Hospital, Eldoret, Kenya. British Journal of Healthcare and Medical Research, 13(3): 94- 109. https://doi.org/10.14738/bjhr.1303.10804. ISSN: 2753-7919.
Pscherer, S., Dippel, F.-W., Lauterbach, S., & Kostev, K. (2012). Amputation rate and risk factors in type 2 patients with diabetic foot syndrome under real-life conditions in Germany. Primary Care Diabetes, 6: 241–246. https://doi.org/10.1055/s-0031-1277548.
Robins, H. (2008). Offloading the diabetic foot ulcer. Wound Healing Southern Africa, 1(2): 18–20.
Sadriwala, Q. S., Gedam, B. S., & Akhtar, M. A. (2018). Risk factors of amputation in diabetic foot infections. International Surgery Journal, 5(4): 1399. https://doi.org/10.18203/2349-2902.isj20181118.
Saleem, S., Hayat, N., Ahmed, I., Ahmed, T., & Gaffar REHAN, A. (2017). Risk factors associated with poor outcome in diabetic foot ulcer patients. Turk J Med Sci, 47: 826–831. https://doi.org/10.3906/sag-1602-119.
Sherman, R. A. (2003). Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy. Diabetes Care, 26(2):446–451. https://doi.org/10.2337/diacare.26.2.446. Scholar Publishing
Singh, N., Armstrong, G., D., & Lipsky A., B. (2005). Preventing foot ulcers in patients with diabetes. The Journal of the American Medical Association, 293: 217–228.
Walrond, E. R. (2001). The Caribbean experience with the diabetic foot management of the diabetic foot. The West Indian Medical Journal, 50 Suppl 1: 24–26.
Wolff, H., & Hansson, C. (2003). Larval therapy-an effective method of ulcer debridement. Clinical and Experimental Dermatology, 28(2): 134–137.
Yazdanpanah, L., Nasiri, M., & Adarvishi, S. (2015). Literature review on the management of diabetic foot ulcers. World Journal of Diabetes, 6(1): 37- 53. https://doi.org/10.4239/wjd.v6.i1.37.PMID: 25685277 . PMCID: PMC4317316.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Obare K. Sophie, Barry R. Ayumba, Neford Ongaro Neford

This work is licensed under a Creative Commons Attribution 4.0 International License.