Preparing Your Manuscript
Preparing Your Manuscript
Structure, reporting guidelines, ethics statements, units, references, figures, tables and declarations.
This guide explains how to prepare each part of your manuscript so that it can be reviewed and published efficiently. It follows practice recommended by leading open-access medical publishers, the recommendations of the ICMJE for the conduct, reporting and publication of scholarly work in medical journals, and the reporting guidelines maintained by the EQUATOR Network. Following it closely improves the clarity and integrity of your work, speeds up review and reduces the chance of your manuscript being returned before assessment.
Manuscript template & reference style
Prepare your manuscript using the shared Scholar Publishing template and numbered reference style.
Download the manuscript template (.dotx) Microsoft Word templateDownload the reference style (.ens) EndNote numbered styleBefore you start
Confirm that your manuscript fits the journal’s Aims & Scope; that it is original and neither published nor under consideration elsewhere; that all authors meet the authorship criteria and have approved it; and that you can provide the ethics, consent and registration statements described in Ethics and Disclosures. Identify the reporting guideline that applies to your study design and prepare your manuscript, and its checklist, accordingly. Prepare the manuscript using the BJHMR template and the required citation style.
Reporting guidelines
Report your study in accordance with the guideline appropriate to its design, and upload the completed checklist with your submission:
| ▸ | CONSORT for randomised controlled trials (with the trial flow diagram); |
| ▸ | STROBE for observational studies (cohort, case–control and cross-sectional); |
| ▸ | PRISMA for systematic reviews and meta-analyses; |
| ▸ | CARE for case reports and case series; |
| ▸ | STARD for diagnostic-accuracy studies and TRIPOD for prediction models; |
| ▸ | SPIRIT for study protocols and CHEERS for health-economic evaluations; |
| ▸ | SRQR or COREQ for qualitative research; and ARRIVE for research involving animals. |
A comprehensive list is maintained by the EQUATOR Network.
Language and writing style
Write in clear, correct and concise English, using either British or American spelling consistently throughout. Prefer plain, direct sentences; use the active voice where it aids clarity; and define every abbreviation at first use. Use person-centred, non-stigmatising and inclusive language when describing patients, participants and populations, and report participant characteristics (such as sex, gender, age and ethnicity) accurately and only where relevant. If English is not your first language, consider professional language editing before submission; language quality does not affect the editorial decision, which is based on scientific and clinical merit.
File format and general layout
| ▸ | Submit an editable file — Microsoft Word (.docx) is recommended; the system also accepts OpenOffice and RTF. Do not submit the main text as a PDF or as images of text. |
| ▸ | Use a single-column layout, a standard readable font (for example 12-point), and 1.5 or double line spacing. |
| ▸ | Insert continuous line numbers and page numbers to help reviewers refer to specific points. |
| ▸ | Keep formatting simple: most layout is applied during typesetting. Use the word processor’s heading styles rather than manual formatting. |
| ▸ | Use SI units, with conventional clinical units in parentheses where helpful. |
Manuscript structure at a glance
Assemble the manuscript in the following order. Each element is described in detail below.
| ▸ | Title page (title, authors, affiliations, ORCID iDs, corresponding author, word count, trial registration) |
| ▸ | Structured abstract and keywords |
| ▸ | Main text (Introduction; Methods; Results; Discussion; Conclusions) |
| ▸ | Declarations and back matter (ethics approval, consent, funding, conflicts, data availability, author contributions, AI use) |
| ▸ | References |
| ▸ | Tables (each with a caption) |
| ▸ | Figure legends, and figures (in the manuscript or as separate files) |
| ▸ | Supplementary material and reporting-guideline checklist (if any) |
Title page
The title page should contain:
| ▸ | Title — concise, specific and informative, indicating the study design where appropriate (for example “…: a randomised controlled trial”); avoid abbreviations. |
| ▸ | Authors — the full name of each author, in the agreed order, with a superscript marker linking each to an affiliation; include academic degrees only if the journal requires them. |
| ▸ | Affiliations — the institution, city and country for each author at the time the work was carried out; note any present address separately. |
| ▸ | ORCID iD for each author (required for the corresponding author; strongly encouraged for all). |
| ▸ | Corresponding author — clearly identified, with a current email address. |
| ▸ | Trial registration — the registry name and registration number for any clinical trial, and the word count. |
Because review is single-blind, you do not need to prepare an anonymised manuscript; author details remain in the manuscript.
Abstract
Provide a structured abstract of about 250–300 words with labelled sections — typically Background (or Objectives), Methods, Results and Conclusions — that can be read and understood on its own. Report the key numerical results with measures of uncertainty (for example confidence intervals) and, for trials, include the registration number. Do not include citations, undefined abbreviations, or figures and tables.
Keywords
Supply 4–6 keywords that describe the content for indexing and discovery. Where possible, choose terms from the U.S. National Library of Medicine’s Medical Subject Headings (MeSH) to aid indexing, avoid simply repeating words already in the title, and separate the keywords with commas.
Main text
Empirical papers should follow the IMRaD structure. Use numbered headings (for example 1, 1.1, 1.1.1) to a maximum of three levels. Reviews, case reports and other article types follow the structure of their reporting guideline (for example CARE for case reports).
Introduction
Summarise the background and rationale, drawing on the relevant literature without an exhaustive review. State what is already known and what remains uncertain, and give the specific objectives or hypotheses of the study.
Methods
Describe the study design; the setting, dates and participants, with eligibility criteria and methods of recruitment or sampling; the interventions, exposures or comparators; the outcomes, with clear definitions of primary and secondary outcomes; the data sources and measurement; the sample-size calculation; and the statistical methods, including how missing data and potential confounding were addressed. State the ethics approval and consent arrangements and, for trials, the registration details and the protocol, cross-referring to Ethics and Disclosures. Report the methods in enough detail for the study to be appraised and, where relevant, replicated.
Results
Report the flow of participants (with a flow diagram for trials and, where relevant, for reviews), the characteristics of the study population, and the findings for each outcome, giving effect estimates with confidence intervals and exact p-values rather than significance thresholds alone. Present results objectively using text supported by tables and figures, without duplicating data, and reserve interpretation for the Discussion.
Discussion
Summarise the key findings; interpret them in the context of the totality of the evidence; consider mechanisms and clinical, public-health or policy implications; and state the limitations, including potential sources of bias and the generalisability of the findings. Avoid claims that the data do not support, and do not overstate clinical applicability.
Conclusions
Provide a concise conclusion that reflects the strength of the evidence and, where appropriate, the implications for practice, policy and future research.
Units, nomenclature, drugs and statistics
| ▸ | Report measurements in SI units, giving conventional clinical units in parentheses where this aids readers. |
| ▸ | Refer to drugs by their International Non-proprietary Name (generic name); a proprietary name may be given once, in parentheses, where relevant, together with the manufacturer for devices and equipment. |
| ▸ | Use approved nomenclature for genes, organisms and anatomical terms, and define all abbreviations at first use. |
| ▸ | Describe the statistical methods fully; report effect sizes with confidence intervals; state the software and version; and ensure the analysis matches the study design and the reporting guideline. |
Tables
| ▸ | Create each table with the word processor’s table function; do not paste tables as images. |
| ▸ | Number tables consecutively in order of citation, and cite each in the text. |
| ▸ | Give each table a concise caption above the table, and define all abbreviations and statistical notation in footnotes; state units in the column headings. |
| ▸ | Keep tables self-explanatory and avoid duplicating material shown in figures. |
Figures, images and patient privacy
| ▸ | Number figures consecutively in order of citation and cite each in the text; supply a caption for every figure in a list of figure legends. |
| ▸ | Supply figures in a high-resolution format suitable for publication — vector formats (EPS, PDF) for charts and line art, and TIFF or high-resolution PNG/JPEG for clinical images, radiographs and photomicrographs; embed any fonts. |
| ▸ | As a guide, provide line art at around 1000–1200 dpi, photographic images at least 300 dpi, and combination images at least 500–600 dpi. |
| ▸ | Patient identifiability: remove all identifying information from images and their metadata; do not use black bars over the eyes, which do not guarantee anonymity. Any potentially identifiable image, description or detail requires the written informed consent of the patient (or next of kin) to publish, as set out in Ethics and Disclosures. |
| ▸ | Image integrity: figures must reflect the original data; do not add, move, obscure, enhance or remove features. Adjustments to brightness or contrast must be applied to the whole image and disclosed, and grouped or spliced images (for example gels or blots) must be made explicit. |
References and citations
| ▸ | Use the journal’s required citation style. The current shared guidance and template use a numbered style, in which references are cited in the text by number in square brackets in order of appearance (for example “as reported previously [5]” or “[1–3, 7]”) and listed consecutively in the order cited. |
| ▸ | Include a DOI, as a full https://doi.org/ link, for every source that has one, and give the PubMed identifier where available. |
| ▸ | Cite only works that are published or accepted for publication; cite personal communications and unpublished data in the text only, not in the reference list. |
| ▸ | Use a reference manager to ensure accuracy; authors are responsible for the correctness of all references, and should avoid excessive or inappropriate self-citation. |
Declarations and back matter
Place the following declarations after the main text and before the references, stating “None” or “Not applicable” where appropriate but omitting none. Full guidance is given on the Ethics and Disclosures page.
| ▸ | Ethics approval — the approving committee and reference number, or a statement of why approval was not required. |
| ▸ | Consent to participate and consent to publish — including written consent for any identifiable patient information or images. |
| ▸ | Trial registration — registry and number for clinical trials. |
| ▸ | Data availability — whether and how the supporting data can be accessed. |
| ▸ | Funding — all sources, with grant numbers, and the funder’s role, or a statement that no specific funding was received. |
| ▸ | Conflicts of interest — financial and non-financial competing interests, or a statement that none exists. |
| ▸ | Author contributions — using the CRediT taxonomy. |
| ▸ | Use of generative AI — any substantive use, naming the tool and version. |
| ▸ | Acknowledgements — non-author contributions (optional), with permission where individuals are named. |
Final checks before submission
Before you submit, run through the Submission Checklist to confirm that your manuscript is complete, follows the relevant reporting guideline, and is accompanied by all ethics, consent and registration statements and by every declaration, and that each table, figure and reference is cited and consistent.
