Listeria Monocytogenes Meningoencephalitis in an Immunocompromised Patient: A Diagnostic and Therapeutic Challenge

Authors

  • I. Nabih Medical Emergency Intensive Care Unit P27, Ibn Rochd University hospital, Casablanca
  • S. Tougar Department of Medical Intensive Care, Ibn Rochd, university hospital, faculty of medicine and pharmacy of Casablanca, Hassan II university, Casablanca, Morocco.
  • S. Alaoui Department of Medical Intensive Care, Ibn Rochd, university hospital, faculty of medicine and pharmacy of Casablanca, Hassan II university, Casablanca, Morocco
  • C. Qasbaoui Department of Medical Intensive Care, Ibn Rochd, university hospital, faculty of medicine and pharmacy of Casablanca, Hassan II university, Casablanca, Morocco
  • Z. Naghir Department of anesthesiology and intensive care medicine, Ibn Rochd, university hospital, faculty of medicine and pharmacy of Casablanca, Hassan II university, Casablanca, Morocco
  • B. Charra Department of Medical Intensive Care, Ibn Rochd, university hospital, faculty of medicine and pharmacy of Casablanca, Hassan II university, Casablanca, Morocco

DOI:

https://doi.org/10.14738/bjhr.1206.18658

Keywords:

Listeria monocytogenes, Neuro-meningeal infection, Immunocompromised patient, Molecular diagnostics

Abstract

Neuro-meningeal listeriosis is a rare CNS infection primarily affecting immunocompromised patients. We report a 25-year-old woman with lupus nephritis on azathioprine, presenting with febrile altered consciousness, gastrointestinal symptoms, and seizures. MRI showed deep temporo-occipital hyperintensities without enhancement. Diagnosis was confirmed by positive blood cultures and CSF multiplex PCR. Treatment with ampicillin and gentamicin led to recovery. This case illustrates the diagnostic challenge of atypical presentations and underscores the importance of combining imaging and molecular diagnostics for timely management.

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Published

2025-12-07

How to Cite

Nabih, I., Tougar, S., Alaoui, S., Qasbaoui, C., Naghir, Z., & Charra, B. (2025). Listeria Monocytogenes Meningoencephalitis in an Immunocompromised Patient: A Diagnostic and Therapeutic Challenge. British Journal of Healthcare and Medical Research, 12(06), 134–139. https://doi.org/10.14738/bjhr.1206.18658

Issue

Vol. 12 No. 06 (2025): British Journal of Healthcare and Medical Research

Section

Original Articles

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Copyright (c) 2025 I. Nabih, S. Tougar, S. Alaoui, C. Qasbaoui, Z. Naghir, B. Charra

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This work is licensed under a Creative Commons Attribution 4.0 International License.