Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome Presenting with Condylomata Acuminata in a 28 Years Old Zambian Woman: A Case Report
DOI:
https://doi.org/10.14738/bjhr.1202.18386Keywords:
Rare, Differences, Sex, Development, Diagnosis, ManagementAbstract
We present a rare form of Differences in sex development (DSD) that presented with Human papilloma virus (HPV) infection. The case is that of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome presenting with condylomata acuminate in a 28 years old Zambian woman. The diagnosis was made clinically and in the operating theatre. The case underscores the importance of taking a thorough gynaecological history and physical examination in all female patients that present with sexually transmitted infections as rare DSD may be missed due to cultural barriers. Imaging techniques are key to confirming the diagnosis of DSD such as MRKH syndrome.
References
Lee PA, Houk CP, Ahmed SF, and Hughes IA (2006). Consensus statement on management of intersex disorders. International consensus conference on intersex. Pediatrics. 118(2): e488-500. 60 Mwanakasale, V., Balapala, K. R., & Kalolekesha, M. C. (2025). Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome Presenting with Condylomata Acuminata in a 28 Years Old Zambian Woman: A Case Report. British Journal of Healthcare and Medical Research, Vol - 12(02). 58-61.
Hauser GA and Schreiner WE (1961). Mayer-Rokitansky- Küster -Hauser Syndrome. Rudimentary solid bipartite uterus with solid vagina. Schweiz Med Wochenschr. 91: 381-384.
Morten Krogh Herlin, Michael Bjørn Petersen, and Mats Brännström (2020). Mayer-Rokitansky- Küster-Hauser syndrome: a comprehensive update. Orphanet J Rare Diseases. 15: 214.
Herlin M, Bjørn A-MB, Rasmussen M, Trolle B, and Petersen MB (2016). Prevalence and patient characteristics of Mayer-Rokitansky-Küster -Hauser Syndrome: a nationwide registry-base. Hum reprod. 31: 2384-2390.
James William D, Elston Dirk, Treat James R, Rosenbach Misha A, and Neuhaus Isaac. 19 viral diseases; genital warts. Andrews’ Diseases of the skin: Clinical Dermatology. (13th Ed). Edinburgh: Elsevier (2020). PP. 406-410.
O’Mahony C, Gomberg M, Skerlev M, Alraddadi A, de Las heras-Alonzo ME, Majewski S, Nicolaidou E, Serdaroglu S, Kutlubay Z, Tawara M, Stary A, Al Hammadi A, and Cusini M (2019). Position statement for the diagnosis and management of anogenital warts. J Eur Acad Dermatol Venereol. 33(6): 1006-1019.
Kaderli R, Schnuriger B, and Brugger LE (2014). The impact of smoking on HPV infection and the development of anogenital warts. Int J Colorectal Dis. 29(8): 899-908.
Kobayashi A and Behringer RR (2003). Developmental genesis of the female reproductive tract in mammals. Nat Rev Genet. 4: 969-980.
Williams LS, Demir Eksi D, Shen Y, Lossie AC, Chorich LP, Sullivan ME, et al. (2017). Genetic analysis of Mayer-Rokitansky- Küster-Hauser syndrome in a large cohort of families. Fertil Steril. 108: 145-151.
Friedler S, Grin L, Liberti G, Saar-Ryss B, Rabinson Y, and Meltzer S (2016). The reproductive potential of patients with Mayer-Rokitansky- Küster-Hauser syndrome using gestational surrogacy: a systematic review. Reprod Biomed Online. 32:54-61.
ACOG committee Opinion. No. 728 (2018): Mujllerian Agenesis: Diagnosis, management, and Treatment. Obstet Gynecol. 131: e35-42.
Davydov S (1969). Colpopoiesis from the peritoneum of the ureterorectal space. Obstet Gynecol. 12: 252-257.
Frank R (1938). The formation of an artificial vagina without operation. Am J Obs Gynecol. 35: 1053-1055
D’Alberton A and Santi F (1972). Formation of a neovagina by coitus. Obstet Gynecol. 40: 763-764.
Lacy CJ, Woodhall SC, Wikstrom A, and Ross J (2012). European guideline for the management of anogenital warts
Scheinfield N, and Lehman DS (2006). An evidence-based review of medical and surgical treatment of genital warts. Dematol. Online J. 12(3): 5.
Meltzer SM, Monk BJ, and Tewari KS (2009). Green tea catechins for treatment of external genital warts. Am J Obstet. Gynecol. 3: 233. E1-7.
Mayeaux EJ and Dunton C. Modern management of external genital warts. J Low Genit Tract Dis (2008). 12(3): 185-
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Victor Mwanakasale, Kartheek R Balapala, Memory C Kalolekesha
This work is licensed under a Creative Commons Attribution 4.0 International License.
