Knowledge of Antimicrobial Drug Resistance (AMR) Among Patients in a General Outpatient Clinic in Abuja Municipal Area Council (AMAC), Federal Capital Territory, Nigeria
DOI:
https://doi.org/10.14738/bjhmr.103.14684Keywords:
Knowledge, Antimicrobial Drug Resistance (AMR), antibiotic resistance, antimicrobial use, Abuja Municipal Area Council (AMAC)Abstract
Background: Antimicrobial resistance (AMR) is currently prevalent and has the potential to affect everyone, of any age, in any country. In humans, animals, and the environment, antimicrobial-resistant microbes are quickly emerging and spreading. This study aims to assess the knowledge of Antimicrobial Drug Resistance (AMR) among patients in a General Outpatient Clinic in Abuja Municipal Area Council (AMAC), Federal Capital Territory, Nigeria. Methods: This was a descriptive cross-sectional study among 400 clients in district hospital done in 2022. A multistage sampling technique was adopted for this study. Data was collected using self-administered structured questionnaire and analyzed and presented as tables, proportions, and percentages using the IBM SPSS 28 (Statistical Package for the Social Sciences) computer software (IBM SPSS Inc. 2021) Ethical approval was granted by Bingham University Teaching Hospital Ethical Research Committee, Jos, Plateau State. Results: The study revealed that the knowledge of antimicrobial resistance between male and female respondents. 8.5% of female respondents had good knowledge, 20.75% had fair knowledge while 27.75% had poor knowledge. Of all the male respondents, 8.5% had good knowledge, 13% had fair knowledge and 21.5% had poor knowledge. Summarily, only 68 (17.0%) of participants had good knowledge of antimicrobial resistance, 135 (33.75%) had fair knowledge of antimicrobial resistance, while 197 (49.25%) had poor knowledge of antimicrobial resistance. Test of association between knowledge of antimicrobial resistance and Sociodemographic showed that Marital Status (χ² (2, N=400) = 44.28, p < 0.045), Education (χ² (2, N=400) = 123.80, p < 0.001) and Age (χ² (2, N=400) = 112.95, p < 0.001) were statistically significant. Conclusion: The Federal, State, and Local governments, health care providers, and community health workers should focus on increasing awareness of AMR risk factors through health campaigns and program that will aid behavioural change.
References
Antibiotic resistance [Internet]. Who.int. 2022 [cited 11 January 2022]. Available from: https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance
World Health Organization. Access to essential medicines, vaccines and health technologies: fact sheet on Sustainable Development Goals (SDGs): health targets. World Health Organization. Regional Office for Europe; 2017.
Foodborne diseases [Internet]. Who.int. 2022 [cited 11 May 2022]. Available from: https://www.who.int/health-topics/foodborne-diseases
European Commission. Action plan against the rising threats from antimicrobial resistance.
Communication from the Commission to the European Parliament and the Council. 2011;15.
European Commission. A European One Health Action Plan Against Antimicrobial Resistance (AMR). 2017.https://ec.europa.eu/health/sites/default/files/antimicrobial_resistance/docs/amr_2017_actionplan.pdf.
McKernan C, Benson T, Farrell S, Dean M. JAC-Antimicrobial Resistance. 2021
Laxminarayan R, Matsoso P, Pant S, Brower C, Røttingen J, Klugman K et al. Access to effective antimicrobials: a worldwide challenge. The Lancet. 2016;387(10014):168-175.
O'Neill J. Tackling a crisis for the health and wealth of nations. London: Review on Antimicrobial Resistance; 2014.
Varma J, Oppong-Otoo J, Ondoa P, Perovic O, Park B, Laxminarayan R et al. Africa Centres for Disease Control and Prevention’s framework for antimicrobial resistance control in Africa. African Journal of Laboratory Medicine. 2018;7(2).
Fairchild A, Bayer R. Ethics and the Conduct of Public Health Surveillance. Science. 2004;303(5658):631-632.
US Department of Health and Human Services. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention. 2013 Apr 23:1-13.
Pharmaceuticals P, spearhead F, use P, study S, migraine P, drug R et al. The bacterial challenge - time to react [Internet]. Worldpharmanews.com. 2022 [cited 11 May 2022]. Available from: https://www.worldpharmanews.com/research/24-regulatory- affairs/ema/942-the-bacterial-challengetime-to-react.
World Health Organization. The evolving threat of antimicrobial resistance: options for action. World Health Organization; 2012.
European Center for Disease control (ECDC), European Emergency Medicines agency (EMEA). The bacterial challenge–time to react a call to narrow the gap between multidrug- resistant bacteria in the eu and development of new antibacterial agents. Solna: ECDC & EMEA Joint Press Release. 2009.
World Health Organization. Tackling antibiotic resistance from a food safety perspective in Europe. World Health Organization. Regional Office for Europe; 2011. https://www.euro.who.int/data/assets/pdf_file/0005/ 136454/e94889.pdf.
Gelband H, Miller-Petrie M, Suraj P, Sumanth G, Levinson J, Barter D, White A, Laxminarayan R. The state of the world's antibiotics, 2015. The state of the world's antibiotics, 2015.
Hadi U, Kolopaking EP, Gardjito W, Gyssens IC, Van den Broek PJ. Antimicrobial resistance and antibiotic use in low-income and developing countries. Folia Medica Indonesiana. 2006 Jul 1;42(3):183-95.
Holloway KA, Henry D. WHO essential medicines policies and use in developing and transitional countries: an analysis of reported policy implementation and medicines use surveys. PLoS medicine. 2014 Sep 16;11(9):e1001724.
India SJ, Ray P, Manchanda V, Bajaj J, Chitnis DS, Gautam V, Goswami P, Gupta V, Harish BN, Kagal A, Kapil A. Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. The Indian journal of medical research. 2013 Feb;137(2):363.
Ghafur A, Mathai D, Muruganathan A, Jayalal JA, Kant R, Chaudhary D, Prabhash K, Abraham OC, Gopalakrishnan R, Ramasubramanian V, Shah SN. The Chennai Declaration: a roadmap to tackle the challenge of antimicrobial resistance. Indian Journal of Cancer. 2013 Jan 1;50(1):71.
Antimicrobial resistance [Internet]. Who.int. 2022 [cited 11 May 2022]. Available from: https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
Essack SY, Desta AT, Abotsi RE, Agoba EE. Antimicrobial resistance in the WHO African region: current status and roadmap for action. Journal of public health. 2017 Mar 1;39(1):8- 13.
Mouiche MM, Moffo F, Akoachere JF, Okah-Nnane NH, Mapiefou NP, Ndze VN, Wade A, Djuikwo-Teukeng FF, Toghoua DG, Zambou HR, Feussom JM. Antimicrobial resistance from a one health perspective in Cameroon: a systematic review and meta-analysis. BMC Public Health. 2019 Dec;19(1):1-20.
Fadare JO, Ogunleye O, Iliyasu G, Adeoti A, Schellack N, Engler D, Massele A, Godman B. Status of antimicrobial stewardship programmes in Nigerian tertiary healthcare facilities: findings and implications. Journal of global antimicrobial resistance. 2019 Jun 1; 17:132-6.
Ghebremedhin B, Olugbosi MO, Raji AM, Layer F, Bakare RA, Konig B, Konig W. Emergence of a communityassociated methicillin-resistant Staphylococcus aureus strain with a unique resistance profile in Southwest Nigeria. Journal of clinical microbiology. 2009 Sep;47(9):2975-80.
Lamikanra A, Crowe JL, Lijek RS, Odetoyin BW, Wain J, Aboderin AO, Okeke IN. Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use. BMC infectious diseases. 2011 Dec;11(1):1-0.
Antimicrobial Use and Resistance in Nigeria. Situation Analysis and Recommendations [Internet]. Ncdc.gov.ng. 2017 [cited 12 May 2022]. Available from: https://ncdc.gov.ng/themes/common/docs/protocols/56_1510840387.pdf
Annan-Prah A, Agbemafle E, Asare PT, Akorli SY. Antibiotic use, abuse and their public health implication: the contributory role of management flaws in the poultry industry in two agro-ecological zones in Ghana.
Egwuenu A, Obasanya J, Okeke I, Aboderin O, Olayinka A, Kwange D, Ogunniyi A, Mbadiwe E, Omoniyei L, Omotayo H, Niyang M. Antimicrobial use and resistance in Nigeria: situation analysis and recommendations, 2017. Pan African Medical Journal. 2018; 21.
Abubakar U. Antibiotic use among hospitalized patients in northern Nigeria: a multicenter point-prevalence survey. BMC infectious diseases. 2020 Dec;20(1):1-9.
World Health Organization. Antibiotic resistance: multi-country public awareness survey.WHO Library Cataloguing-in-Publication Data. Geneva; ISBN 978 92 4 150981 7. 2015. Available from https://www.who.int/rugresistance/documents/baselinesurveynov2015/en.pdfhttp://apps.who.int/medicinedocs/documents/s22245en/s22245en.pdf
Boxall A, Wilkinson J. Identifying hotspots of resistance selection from antibiotic exposure in urban 142 environments around the world. InSETAC Europe 29th Annual Meeting, Helsinki 2019 May 27.
Africa Center for Disease Control. Africa CDC framework for antimicrobial resistance, 2018- 2023. Currently
Global action plan on antimicrobial resistance [Internet]. World Health Organization. World Health Organization; 2015. Available from: https://www.who.int/publications-detail redirect/9789241509763
World Health Organization. Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report -Early Implementation 2020
National Bureau of Statistics (2020). Demographic statistics bulletin. [cited 11 May 2022] pp. 9.S https://nigerianstat.gov.ng/elibrary
National Population Commission [Nigeria]. 2010. Population distribution by age and sex. The 2006 population and housing census priority table volume (IV). Abuja: NPC
Dawan PD. Brief history of the creation of Federal capital territory (FCT). PD Dawan (Ed). 2000.
Abuja Municipla Area Council (AMAC), Amac.knowfct.com. 2022. About AMAC–AMAC. [online]Available at:<http://amac.knowfct.com/about-amac/> [Accessed 23 May 2022].
Adakayi, P.E. (2000). Climate. In Dawan, P. D. (ed.). Geography of Abuja Federal Capital Territory. Famous/Asanlu Publishers, Minna, Niger State, Nigeria, pp. 9-23.
Federal Ministry of Health, World Health Organization. National Drug Policy. 2005.
42.Maitamadh.com.ng. 2022. Home. [online] Available at: <https://maitamadh.com.ng/> [Accessed 23 May 2022]. 43. Cochran WG. Sampling techniques. John Wiley & Sons; 1977.
Herawati, F., Setiasih, Alhabsyi, M. M., Gunawan, W., Palijama, D. E., Diah, L. F., Avanti, C. (2019). A patient caregiver survey in Indonesia: Knowledge and perception of antibiotic use and microbial resistance. J Infect Public Health, 1(19), 006.
Grigoryan L, Burgerhof JG, Degener JE, Deschepper R, Lundborg CS, Monnet DL, Scicluna EA. Attitudes, beliefs and knowledge concerning antibiotic use and self-medication: a comparative European study y. pharmacoepidemiology and drug safety. 2007; 16:1234-43.
Corbett, K. K., Gonzales, R., Leeman-Castillo, B. A., Flores, E., Maselli, J., & Kafadar, K. (2005). Appropriate antibiotic use: variation in knowledge and awareness by Hispanic ethnicity and language. Preventive medicine, 40(2), 162-169.
Gebrekirstos NH, Workneh BD, Gebregiorgis YS, Misgina KH, Weldehaweria NB, Weldu MG, Belay HS. Nonprescribed antimicrobial use and associated factors among customers in drug retail outlet in Central Zone of Tigray, northern Ethiopia: a cross-sectional study. Antimicrobial Resistance & Infection Control. 2017 Dec;6(1):1-0.
Peng, D., Wang, X., Xu, Y., Sun, C., & Zhou, X. (2018). Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey. Glob Health Action, 11(1), 1496973.
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