Non-invasive Diabetes Detection using Metabolic Heat Conformation Technology and Heart Rate

Authors

  • Toshifumi Tanaka Kyushu Institute of Technology
  • Ryo Takeuchi Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology
  • Hiroyuki Miyamoto Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology

DOI:

https://doi.org/10.14738/jbemi.91.11516

Keywords:

Diabetes detection, Non-invasive, Metabolic heat conformation technology, Heart rate, Machine Learning Technique

Abstract

Screening and early detection of type 2 diabetes are important to prevent diabetic complications. Commonly, type 2 diabetes is detected by blood glucose measurement. However, the compliance for existing invasive devices is insufficient because these devices can potentially cause pain, infection, and tissue damage due to needle use. Thus, we have been developing a non-invasive diabetes detection method that uses metabolic heat conformation (MHC) technology. Our previous method using only MHC technology could not detect diabetes accurately, therefore, a novel non-invasive diabetes detection method using additional bio-signal needed to be developed to improve accuracy of early diabetes detection. Heart rate is considered as an additional bio-signal which can be measured by non-invasive devices. The previous studies report that there is a relation between heart rate and diabetes. The objective of this study is to propose a novel non-invasive diabetes detection method using both MHC technology and heart rate. The proposed method detects diabetes by machine learning technique using skin surface temperature data based on MHC technology and heart rate. In the experiment, the proposed method and our previous method were compared by using 95 samples bio-signal dataset obtained from 5 participants including 2 diabetes patients. The results showed that the proposed method could detect diabetes with accuracy higher than 90 %, which is significant improvement in comparison to our previous method, which detected diabetes with accuracy less than 80 %. The results support the possibility that the proposed method using both MHC technology and heart rate can be applied for non-invasive early diabetes detection.

References

Zhou, B., et al., Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants. The Lancet, 2016, 387(10027): p. 1513-1530.

David, C, Why screen for type 2 diabetes?. Diabetes research and clinical practice, 2016, 121: p. 215-217.

So, C.F., et al., Recent advances in noninvasive glucose monitoring. Medical Devices (Auckland, NZ), 2012, 5: p. 45.

Yasuhiro, U., et al., Noninvasive blood glucose measurement. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, 2018, p. 489-504.

Villena, G., et al., The progress of glucose monitoring-A review of invasive to minimally and non-invasive techniques, devices and sensors. Sensors, 2019, 19(4): p. 800.

Li, D. C., et al., Glucose measurement using surface plasmon resonance sensor with affinity based surface modification by borate polymer. 2015 Transducers-2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS). 2015, p. 1569-1572.

Ryo, T., et al., Non-Invasive Diabetes Prediction Method Based on Metabolic Heat Conformation Theory and Machine Learning. Journal of Mechanical and Electrical Intelligent System. 2021, 4(1): p. 42-19.

Kit, S.Y.H., et al., Non-invasive blood glucose measurement using temperature-based approach. Jurnal Teknologi, 2013, 64(3): p. 105-110.

Cho, O.K., et al., Noninvasive measurement of glucose by metabolic heat conformation method. Clinical chemistry, 2004, 50(10): p. 1894-1898.

Tang, F., et al., Non-invasive glucose measurement by use of metabolic heat conformation method. Sensors, 2008, 8(5): p. 3335-3344.

Ryo, T., et al., Proposal of Blood Glucose Control and Exercise Therapy Support System Using Non-invasive Blood Glucose Meter. Pertanika Journal of Science & Technology, 2020, 28(S2): p. 13-24.

Ryo, T., et al., Proposal of Blood Glucose Prediction Method Based on MHC Theory. The 8th IIAE International Conference on Industrial Application Engineering 2020, 2020, p. 44-49.

Thomas, B., et al., Heart rate variability in type 2 diabetes mellitus: A systematic review and meta-analysis. PloS one, 2018, 13(4): p. e0195166.

Rosa, E.A-C., et al., Heart rate variability as early biomarker for the evaluation of diabetes mellitus progress. Journal of diabetes research, 2016, 2016: p. 8483537.

Kudat, H., et al., Heart rate variability in diabetes patients. Journal of international medical research, 2006, 34(3): p. 291-296.

El-Amrawy, F., et al., Are currently available wearable devices for activity tracking and heart rate monitoring accurate, precise, and medically beneficial?. Healthcare informatics research, 2015, 21(4): p. 315-320.

Cheatham, S.W., et al., Concurrent validity of resting pulse-rate measurements: a comparison of 2 smartphone applications, the polar H7 belt monitor, and a pulse oximeter with bluetooth. Journal of sport rehabilitation, 2015, 24(2): p. 171-178.

Kavakiotis, I., et al., Machine learning and data mining methods in diabetes research. Computational and structural biotechnology journal, 2017, 15: p. 104-116.

Pronab, G., et al., A Comparative Study of Different Machine Learning Tools in Detecting Diabetes. Procedia Computer Science, 2021, 192: p. 467-477.

Dagliati, A., et al., Machine learning methods to predict diabetes complications. Journal of diabetes science and technology, 2018, 12(2): p. 295-302.

Le, C.S., et al., Ridge estimators in logistic regression. Journal of the Royal Statistical Society: Series C (Applied Statistics), 1992, 41(1): p. 191-201. 87

Downloads

Published

2022-02-19

How to Cite

Tanaka, T., Takeuchi, R., & Miyamoto, H. (2022). Non-invasive Diabetes Detection using Metabolic Heat Conformation Technology and Heart Rate. British Journal of Healthcare and Medical Research, 9(1), 81–87. https://doi.org/10.14738/jbemi.91.11516