Environmental Factors Impacting Heavy Metal Contamination of Mango Fruits and Health Implications on Consumers: A Biochemical Analysis
DOI:
https://doi.org/10.14738/bjhr.1304.12020Keywords:
Mango, Mangifera indica, heavy metals, environmental pollution, toxicity, public healthAbstract
Mango (Mangifera indica L) is a cherished fruit in many continents. It has a high trade value and economic importance due to its production and sales. However, anthropogenic activities have often impacted the quality, creating contaminated fruits for human consumption. This review of recent literature highlights the staple nature of the fruit and its contributions to the caloric value of its consumers. However, different environmental practices, ranging from natural causes to anthropogenic activities such as industrial production, agrochemical uses and discharges, vehicular traffic, create sources of pollution to the mango fruit. Fruit contamination is rampant in Africa and Asia, predisposing consumers to chronic toxicity. The public health impact may be through pathologies initiated by heavy metal poisoning owing to accumulation in different body tissues such as bones, brain, liver, and kidneys. Molecular basis for heavy metals update and toxicities were discussed. Proactive and corrective strategies were made to manage agricultural soils and safeguard the public from consuming heavy metals-contaminated mangoes.
References
Adebayo, O. T., Olayanju, T. M., and Oladipo, O. (2020). Food safety and heavy metal contamination in fruits and vegetables: Challenges in developing countries. Environmental Monitoring and Assessment, 192(7), 1–13. https://doi.org/10.1007/s10661-020-8287-4
Ahmed, S., Khan, M., and Iqbal, J. (2019). Nutritional and medicinal importance of mango fruit: A review. Journal of Food Science and Nutrition, 7(2), 45–56.
Alloway, B. J. (2017). Heavy metals in soils: Trace metals and metalloids in soils and their bioavailability (3rd ed.). Springer.
Alloway, B. J. (2019). Heavy metals in soils: Trace metals and metalloids in soils and their bioavailability (4th ed.). Springer. https://doi.org/10.1007/978-3-030-30759-2
Antoine, J. M. R., Fung, L. A. H., and Grant, C. N. (2017). Assessment of the potential health risks associated with the consumption of fruits and vegetables grown in contaminated soils. Food and Chemical Toxicology, 107, 300–311. https://doi.org/10.1016/j.fct.2017.07.044 Scholar Publishing
Arnot, J. A., and Gobas, F. A. P. C. (2017). A review of bioconcentration, bioaccumulation, and biomagnification of organic chemicals in aquatic environments. Environmental Reviews, 25(1), 1–19. https://doi.org/10.1139/er-2016-0047
Barberon, M., and Geldner, N. (2014). Radial transport of nutrients: The plant root as a polarized epithelium. Plant Physiology, 166(2), 528–537. https://doi.org/10.1104/pp.114.246124
Burkhard, L. P., Arnot, J. A., Embry, M. R., Farley, K. J., Hoke, R. A., Kitano, M., Leslie, H. A., Lotufo, G. R., Parkerton, T. F., Sappington, K. G., and Tomy, G. T. (2019). Comparing laboratory and field measured bioaccumulation endpoints. Integrated Environmental Assessment and Management, 15(1), 54–65. https://doi.org/10.1002/ieam.4105
Chen, H., Teng, Y., Lu, S., Wang, Y., and Wang, J. (2019). Contamination features and health risk of soil heavy metals in China. Science of the Total Environment, 512–513, 143–153. https://doi.org/10.1016/j.scitotenv.2015.01.025
Clarkson, T. W., and Magos, L. (2020). The toxicology of mercury and its chemical compounds. Critical Reviews in Toxicology, 50(1), 1–39. https://doi.org/10.1080/10408444.2020.1798591
Clemens, S., and Ma, J. F. (2016). Toxic heavy metal and metalloid accumulation in crop plants and foods. Annual Review of Plant Biology, 67, 489–512. https://doi.org/10.1146/annurev-arplant-043015-112301
Codex Alimentarius Commission. (2020). Codex General Standard for Contaminants and Toxins in Food and Feed (CXS 193-1995, Rev. 2020). FAO/WHO. https://www.fao.org/fao-whocodexalimentarius/codex-texts/dbs/en/
European Commission. (2020). Commission Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs.
Food and Agriculture Organization of the United Nations. (2022). FAOSTAT statistical database: Crops and livestock products. FAO.
Godt, J., Scheidig, F., Grosse-Siestrup, C., Esche, V., Brandenburg, P., Reich, A., and Groneberg, D. A. (2018). The toxicity of cadmium and resulting hazards for human health. Journal of Occupational Medicine and Toxicology, 13(1), 1–19. https://doi.org/10.1186/s12995-018-0192-3
Hinsinger, P., Bengough, A. G., Vetterlein, D., and Young, I. M. (2021). Rhizosphere: Biophysics, biogeochemistry and ecological relevance. Plant and Soil, 463(1–2), 1–18. https://doi.org/10.1007/s11104-021-04934-9
Ismael, M. A., Elyamine, A. M., Moussa, M. G., Cai, M., Zhao, X., and Hu, C. (2019). Cadmium in plants: Uptake, toxicity, and detoxification mechanisms. Environmental Science and Pollution
Ismael, M. A., Elyamine, A. M., Moussa, M. G., Cai, M., Zhao, X., and Hu, C. (2020). Cadmium in Plants: Uptake, Toxicity, and Detoxification Mechanisms. Plants, 9(2), 223. https://doi.org/10.3390/plants9020223
Izah, S.C, Iyiola, A.O., Yarkwan, B., Richard, G. (2023). Impact of air quality as a component of climate change on biodiversity-based ecosystem services. In: Srivastav AL et al. (eds): Visualization Techniques for Climate Change with Machine Learning and Artificial Intelligence, Elsevier, Armsterdam, Netherlands. Pp123-147. DOI:https://doi.org/10.1016/B978-0-323-99714-0.00005-4
Jaishankar, M., Tseten, T., Anbalagan, N., Mathew, B. B., and Beeregowda, K. N. (2014). Toxicity, mechanism, and health effects of some heavy metals. Interdisciplinary Toxicology, 7(2), 60–72. https://doi.org/10.2478/intox-2014-0009
Jomova, K., and Valko, M. (2011). Advances in metal-induced oxidative stress and human disease. Toxicology, 283(2–3), 65–87. https://doi.org/10.1016/j.tox.2011.03.001
Scholar Publishing Kabata-Pendias, A. (2019). Trace elements in soils and plants (4th ed.). CRC Press.
Karanja, F., Wanjohi, R., and Mwangi, J. (2020). Assessment of heavy metals in mango fruits grown along major highways in Kenya. African Journal of Food, Agriculture, Nutrition and Development, 20(3), 16200–16215. https://doi.org/10.18697/ajfand.88.19553
Khan, S., Cao, Q., Zheng, Y. M., Huang, Y. Z., and Zhu, Y. G. (2020). Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing, China. Environmental Pollution, 152(3), 686–692. https://doi.org/10.1016/j.envpol.2007.06.056
Khan, Z. I., Ahmad, K., Ashfaq, A., Mehmood, N., and Wajid, K. (2021). Heavy metal accumulation and distribution in edible fruit tissues grown under contaminated conditions. Environmental Monitoring and Assessment, 193(6), 1–14. https://doi.org/10.1007/s10661-021-09143-5
Krämer, U. (2020). Metal hyperaccumulation in plants. Annual Review of Plant Biology, 71, 489–515. https://doi.org/10.1146/annurev-arplant-050718-100508
Li, Z., Ma, Z., van der Kuijp, T. J., Yuan, Z., and Huang, L. (2021). A review of soil heavy metal pollution from mines in China: Pollution and health risk assessment. Science of the Total Environment, 468–469, 843–853. https://doi.org/10.1016/j.scitotenv.2013.08.090
Liu, Y., and Wang, H. (2018). Bioactive compounds in mango and their health benefits. Food Chemistry, 240, 83–91. https://doi.org/10.1016/j.foodchem.2017.07.042
Luo, L., Ma, Y., Zhang, S., Wei, D., and Zhu, Y. G. (2019). An inventory of trace element inputs to agricultural soils in China. Journal of Environmental Management, 246, 498–506. https://doi.org/10.1016/j.jenvman.2019.05.094
National Agency for Food and Drug Administration and Control (NAFDAC). (n.d.). Heavy Metals in Foods Standards.
Naujokas, M. F., Anderson, B., Ahsan, H., Vasken Aposhian, H., Graziano, J. H., Thompson, C., and Suk, W. A. (2013). The broad scope of health effects from chronic arsenic exposure: Update on a worldwide public health problem. Environmental Health Perspectives, 121(3), 295–302. https://doi.org/10.1289/ehp.1205875
Needleman, H. (2019). Lead poisoning. Annual Review of Medicine, 70, 1–11. https://doi.org/10.1146/annurev-med-042617-105526
Olayanju, T. M., Adebayo, O. T., and Oladipo, O. (2019). Heavy metal contamination in mango fruits from industrial and urban zones in southwestern Nigeria. Environmental Science and Pollution
Oluwafemi, A., Adeoye, O., and Eze, P. (2021). Heavy metal contamination in fruits and vegetables from urban and peri-urban farming in Nigeria. Environmental Monitoring and Assessment, 193(6), 345. https://doi.org/10.1007/s10661-021-09115-2
Onuorah, E. N., Chukwuemeka, O., and Ezeh, C. (2021). Regulatory frameworks and heavy metal contamination in fruits: Evidence from Nigeria. Journal of Food Safety, 41(3), e12933. https://doi.org/10.1111/jfs.12933
Peralta-Videa, J. R., López, M. L., Narayan, M., Saupe, G., and Gardea-Torresdey, J. L. (2019). The biochemistry of environmental heavy metal uptake by plants. Journal of Hazardous Materials, 364, 588–599. https://doi.org/10.1016/j.jhazmat.2018.10.053
Qadir, M., Wichelns, D., Raschid-Sally, L., McCornick, P. G., Drechsel, P., Bahri, A., and Minhas, P. S. (2020). The challenges of wastewater irrigation in developing countries. Agricultural Water Management, 152, 97–109. https://doi.org/10.1016/j.agwat.2014.05.017
Rădulescu, A., Lundgren, S. A pharmacokinetic model of lead absorption and calcium competitive dynamics. Sci Rep 9, 14225 (2019). https://doi.org/10.1038/s41598-019-50654-7 Scholar Publishing
Rahman, M. M., Islam, M. R., and Hossain, M. A. (2019). Mercury accumulation in mango fruits irrigated with wastewater in Bangladesh. Journal of Environmental Protection, 10(6), 689–699. https://doi.org/10.4236/jep.2019.106041
Rehman, Z. U., Khan, S., Qin, K., Brusseau, M. L., Shah, M. T., and Din, I. (2018). Quantification of heavy metals in fruits and vegetables and associated health risks. Environmental Geochemistry and Health, 40(4), 1241–1257. https://doi.org/10.1007/s10653-017-9941-6
Reimann, C., and Garrett, R. G. (2017). Geochemical background—Concept and reality. Science of the Total Environment, 350(1–3), 12–27. https://doi.org/10.1016/j.scitotenv.2005.01.047
Ribeiro, S. M. R., Barbosa, L. C. A., Queiroz, J. H., Knödler, M., and Schieber, A. (2020). Phenolic compounds and antioxidant capacity of Brazilian mango (Mangifera indica) varieties. Food Chemistry, 308, 125609. https://doi.org/10.1016/j.foodchem.2019.125609
Riesen, O., and Feller, U. (2020). Redistribution of mineral nutrients via phloem transport in plants. Journal of Plant Nutrition and Soil Science, 183(4), 353–364. https://doi.org/10.1002/jpln.201900385
Risher, J. F., De Rosa, C. T., and Mercury, A. (2010). Mercury exposure: Evaluation and intervention. Environmental Health Perspectives, 118(2), 220–226. https://doi.org/10.1289/ehp.0900912
Rizwan, M., Ali, S., Qayyum, M. F., Arshad, M., Ibrahim, M., Zia-Ur-Rehman, M., ... and Mahmood, K. (2019). Effect of soil amendments on immobilization of heavy metals and reduction in their uptake by crops: A review. Environmental Pollution, 246, 68–80. https://doi.org/10.1016/j.envpol.2018.11.007
Shahid, M., Khalid, S., Abbas, G., Shahid, N., Nadeem, M., Sabir, M., Aslam, M., and Dumat, C. (2020). Heavy metal stress and crop productivity. Environmental Science and Pollution Research, 27(20), 24604–24624. https://doi.org/10.1007/s11356-020-09019-1
Sharma, R. K., Agrawal, M., and Marshall, F. M. (2018). Heavy metal contamination in mango fruits: A study in peri-urban areas of northern India. Environmental Monitoring and Assessment, 190(2), 96. https://doi.org/10.1007/s10661-017-6413-4
Sharma, R. K., Agrawal, M., and Marshall, F. M. (2021). Heavy metal contamination of soil and vegetables in suburban areas: A review. Environmental Pollution, 269, 116088. https://doi.org/10.1016/j.envpol.2020.116088
Singh, R., Kumar, V., and Prasad, S. (2020). Variability in heavy metal accumulation among mango varieties and implications for food safety. Environmental Science and Pollution Research, 27(35), 44321–44333. https://doi.org/10.1007/s11356-020-10478-9
Singh, S., Parihar, P., Singh, R., Singh, V. P., and Prasad, S. M. (2018). Heavy metal tolerance in plants: Role of transcriptomics, proteomics, metabolomics, and ionomics. Frontiers in Plant Science, 9, 1–15. https://doi.org/10.3389/fpls.2018.00855
Tak, H. I., Ahmad, T., and Babu, M. (2018). Overview of phosphate (Pi) transport in plants. International Journal of Molecular Sciences, 19(7), 1914. https://doi.org/10.3390/ijms19071914
Tchounwou, P. B., Yedjou, C. G., Patlolla, A. K., and Sutton, D. J. (2017). Heavy metal toxicity and the environment. EXS, 101, 133–164. https://doi.org/10.1007/978-3-7643-8340-4_6
Tóth, G., Hermann, T., Da Silva, M. R., and Montanarella, L. (2016). Heavy metals in agricultural soils of the European Union. Environment International, 88, 299–309. https://doi.org/10.1016/j.envint.2015.12.017
Scholar Publishing US FDA. (2022). Guidance for Industry: Action Levels for Poisonous or Deleterious Substances in Human Food.
Uzu, G., Sobanska, S., Sarret, G., Muñoz, M., and Dumat, C. (2018). Foliar lead uptake by lettuce exposed to atmospheric pollution. Environmental Science and Technology, 52(22), 13567–13575. https://doi.org/10.1021/acs.est.8b04393
Woldetsadik, D., Drechsel, P., Keraita, B., Itanna, F., and Gebrekidan, H. (2021). Heavy metal accumulation and health risk assessment of fruits and vegetables grown in urban and peri-urban agriculture. Environmental Monitoring and Assessment, 193(2), 1–15. https://doi.org/10.1007/s10661-020-08725-3
World Health Organization (WHO). (2017). Food safety and heavy metals: Public health guidance. Geneva: WHO Press.
World Health Organization (WHO). (2021). Evaluation of certain food contaminants: Seventy-fourth report of the Joint FAO/WHO Expert Committee on Food Additives. Geneva: WHO.
World Health Organization. (2021). Evaluation of certain food contaminants: Seventy-fourth report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series 1028. Geneva: WHO.
Yarkwan, B. and Apeh, D. (2015). Assessment of heavy metals accumulation in tissues of Tilapia zilli and Clarias gariepinus found in Lake Akpoko and River Benue, Nigeria. J. Env. Earth Sci. 5(10): 99-106
Yarkwan, B. (2023). Contamination of African water resources: impacts on biodiversity and strategies for conservation and restoration. In: Izah SC and Ogwu MC (Eds): Sustainable utilization of Africa’s Biological resources and Environment. Springer, pp. 469-496. 888, https://doi.org/10.1007/978-981-19-6974-4_17
Yarkwan, B., Isaac, T.O., Okopi, A., Izah, S.C. (2024). Evidence of the Toxic Potentials of Agrochemicals on Human Health and Biodiversity: Carcinogens and Mutagens. In: Ogwu, M.C., Izah, S.C., Ntuli, N.R. (eds) Food Safety and Quality in the Global South. Springer, Singapore. https://doi.org/10.1007/978-981-97-2428-4_11
Zhang, H., Li, Y., Wang, X., and Chen, Z. (2021). Heavy metal accumulation and health risk assessment of fruits grown in contaminated agricultural soils. Environmental Science and Pollution
Zhang, X., Yang, L., Li, Y., Li, H., Wang, W., and Ye, B. (2018). Impacts of lead/zinc mining and smelting on the environment and human health. Environmental Monitoring and Assessment, 184(4), 2261–2273. https://doi.org/10.1007/s10661-011-2115-6
Zhao, F. J., Ma, Y., Zhu, Y. G., Tang, Z., and McGrath, S. P. (2020). Soil contamination in China: Current status and mitigation strategies. Environmental Science and Technology, 49(2), 750–759. https://doi.org/10.1021/es5047099
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