Perioperative Acute Renal Failure at Chu-Kara
DOI:
https://doi.org/10.14738/bjhr.1201.18072Keywords:
perioperative acute renal failure, CHU-Kara, TogoAbstract
The aim of this study was to take stock of perioperative acute renal failure (ARF) in intensive care at Kara University Hospital. This was a retrospective, descriptive and analytical study of the records of patients with renal failure in the surgical intensive care unit of Kara University Hospital from 1 January 2021 to 31 December 2023. The parameters studied were: epidemiological, diagnostic, therapeutic and evolutionary aspects. Results: 94 cases of ARF were studied, with a frequency of 2.11%. The average age of the patients was 45.65 ± 20.02 years. The most common age group was elderly patients aged 60 and over. The sex ratio was 4.7. The majority of patients were rural (71.30%). The most common type of ARF was functional ARF (76%), followed by obstructive ARF (18%). Digestive surgery was the most common in 60.63% of cases, followed by uronephrological surgery (19.1%) and traumatological surgery (11.7%). General anaesthesia was most common, accounting for 85.10% of cases. The average length of stay in intensive care was 4.25 ±6.42 days. Complications accounted for 40.42% of cases, dominated by infections and hyperkalaemia. Management was associated with a high mortality rate of 31.91%. Conclusion: Perioperative ARF was the result of a combination of numerous factors related to the patient's condition, delay in consultation, type of surgery, precarious haemodynamic events and perioperative infections. Management of perioperative acute renal failure is primarily preventive and aetiological.
References
Bellomo R, Kellum JA, Ronco C. Defining acute renal failure: physiological principles. Intensive Care Med. 1 Jan 2004 ;30(1) :33-7.
Gao X, Wu Y. Perioperative acute kidney injury: The renoprotective effect and mechanism of dexmedetomidine. Biochemical and Biophysical Research Communications. 5 Feb 2024; 695:149402.
Klouche K, Sandapa D, Barrau H, Jonquet O. Insuffisance rénale aiguë en réanimation - Prévention et traitement. Réanimation. 1 Jan 2011;20(2):552-9.
Ephraim RK, Awuku YA, Tetteh-Ameh I, Baffe C, Aglagoh G, Ogunajo VA, et al. Acute kidney injury among medical and surgical in-patients in the Cape Coast Teaching Hospital, Cape Coast, Ghana: a prospective cross-sectional study. Afr Health Sci. June 2021;21(2):795-805.
De Guglielmo W, Rebibou JM, Aho S, Rogier T, Nuemi G, Girard C, et al. Pre-Operative Factors Associated with the Occurrence of Acute Kidney Injury in Patients Aged 65 Years and Over Undergoing Non-Ambulatory Non-Cardiac Surgery. Healthcare (Basel). March 16, 2022;10(3):558.
O'Connor ME, Kirwan CJ, Pearse RM, Prowle JR. Incidence and associations of acute kidney injury after major abdominal surgery. Intensive Care Med. Apr 2016;42(4):521-30.
Shiba A, Uchino S, Fujii T, Takinami M, Uezono S. Association Between Intraoperative Oliguria and Acute Kidney Injury After Major Noncardiac Surgery. Anesth Analg. nov 2018;127(5):1229-35.
Lei VJ, Luong T, Shan E, Chen X, Neuman MD, Eneanya ND, et al. Risk Stratification for Postoperative Acute Kidney Injury in Major Noncardiac Surgery. JAMA Netw Open. Dec 2, 2019;2(12): e1916921.
BENLAMKADAM S. Postoperative acute renal failure. these52-19.pdf [Internet]. [cited 8 May 2024]. Available from: http://wd.fmpm.uca.ma/biblio/theses/annee-htm/FT/2019/these52-19.pdf
Rossouw E, Chetty S. Acute kidney injury after major non-cardiac surgery: Incidence and risk factors. S Afr Med J. March 2, 2023;113(3):135-40.
Raji YR, Ajayi SO, Ademola AF, Lawal TA, Ayandipo OO, Adigun T, et al. Acute kidney injury among adult patients undergoing major surgery in a tertiary hospital in Nigeria. Clin Kidney J. August 2018;11(4):443-9.
Ouro-Bang'Na Maman AF, Agbétra N, Egbohou P, Sama H, Chobli M. Perioperative morbidity and mortality in a developing country: experience of Lomé University Hospital (Togo). Annales Françaises d'Anesthésie et de Réanimation. 1 Dec 2008;27(12):1030-3.
Parikh CR, Devarajan P, Zappitelli M, Sint K, Thiessen-Philbrook H, Li S, et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephrol. Sept 2011;22(9):1737-47.
Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. July 2002 ;62(1) :237-44.
Kadam VR, Loo V, Edwards S, Hewett P. Incidence of acute kidney ınjury during the perioperative period in the colorectal division of surgery - Retrospective study. Indian J Anaesth. Oct 2020 ;64(10) :894-7. Mouzou, E. (2025). Perioperative Acute Renal Failure at Chu-Kara. British Journal of Healthcare and Medical Research, Vol - 12(01). 07-27.
Corinne Isnard Bagnis GD. Department of Nephrology, Pitié-Salpêtrière Hospital, 47-83, boulevard de hospital, 75013 Paris, France. ResearchGate. 8mars2008;121‑31.
Liangos O, Wald R, O'Bell JW, Price L, Pereira BJ, Jaber BL. Epidemiology and outcomes of acute renal failure in hospitalized patients: a national survey. Clin J Am Soc Nephrol. Jan 2006;1(1):43-51.
Grams ME, Sang Y, Coresh J, Ballew S, Matsushita K, Molnar MZ, et al. Acute Kidney Injury After Major Surgery: A Retrospective Analysis of Veterans Health Administration Data. Am J Kidney Dis. June 2016;67(6):872-80.
Ahoui S, Hodonou A, Alexandre A, Blaise T, Vigan J, Roméo A, et al. Insuffisance Rénale Aiguë Post-Opératoire au Centre Hospitalier Universitaire Et Départemental Du Borgou: Fréquence Et Facteurs De Risques Associés. European Scientific Journal. 30 Nov 2016 ;12.
Chertow GM, Lazarus JM, Christiansen CL, Cook EF, Hammermeister KE, Grover F, et al. Preoperative renal risk stratification. Circulation. Feb 18, 1997;95(4):878-84.
Tomozawa A, Ishikawa S, Shiota N, Cholvisudhi P, Makita K. Perioperative risk factors for acute kidney injury after liver resection surgery: an historical cohort study. Can J Anaesth. Jul 2015;62(7):753-61.
MacKenzie CR, Charlson ME. Assessment of perioperative risk in the patient with diabetes mellitus. Surg Gynecol Obstet. Oct 1988;167(4):293-9.
Brivet FG, Kleinknecht DJ, Loirat P, Landais PJ. Acute renal failure in intensive care units--causes, outcome, and prognostic factors of hospital mortality; a prospective, multicenter study. French Study Group on Acute Renal Failure. Crit Care Med. Feb 1996;24(2):192-8.
de Mendonça A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli M, et al. Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med. July 2000;26(7):915-21.
Matuszkiewicz-Rowińska J, Małyszko J. Acute kidney injury, its definition, and treatment in adults: guidelines and reality. Pol Arch Intern Med. 22 Dec 2020 ;130(12) :1074-80.
Himmelfarb J, Joannidis M, Molitoris B, Schietz M, Okusa MD, Warnock D, et al. Evaluation and initial management of acute kidney injury. Clin J Am Soc Nephrol. July 2008;3(4):962-7.
Perioperative renal protection. Perioperative acute renal failure. Recommendations of the jury - long text. Annales Françaises d'Anesthésie et de Réanimation. Feb 2005;24(2):87-119.
Tavernier B, Makhotine O, Lebuffe G, Dupont J, Scherpereel P. Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotension. Anesthesiology. déc 1998 ;89(6) :1313-21.
Pickkers P, Darmon M, Hoste E, Joannidis M, Legrand M, Ostermann M, et al. Acute kidney injury in the critically ill: an updated review on pathophysiology and management. Intensive Care Med. August 2021 ;47(8):835-50.
J. Liotie B. Souweine P. Deteix. Acute renal failure due to drugs. EM-Consulte. 01/01/04 [18-059-M-10]. Masson E
I. Failal, S. Ezzaki, N. Mtioui, S.S. Elkhayat, M. Zamed, G. Medkouri, M. Benghanem, et al. Acute renal failure: epidemiological, aetiological, therapeutic and evolutionary profile. Service de Néphrologie - Hémodialyse et Transplantation Rénale CHU Ibn Rochd, Casablanca, Morocco. 326apr J.-C.
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